Licorice Plus

Support for Cortisol Metabolism*

Licorice Plus is designed for individuals who have been exposed to moderate or prolonged stress and have difficulty achieving an adaptive response, which may be due to physically exhausted reserves.*


  • Supports healthy cortisol metabolism, which is associated with a healthy physiological response to stress*
  • Promotes healthy adrenal function and vitality*
  • Features ashwagandha, an Ayurvedic herb with adaptogenic properties—often referred to as “Indian ginseng”*
  • Standardized to ensure controlled delivery of glycyrrhizic acid—a key active ingredient from licorice
- 60 Tablets
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Recommendations: Take one tablet daily or as directed by your healthcare practitioner.

Serving Size:

Licorice Plus - 60 Tablets

Ingredient Amount Daily Value
Licorice (Glycyrrhiza glabra) Root Extract [standardized to 25% (75 mg) glycyrrhizic acid] 300 mg 
Ashwagandha (Withania somnifera) Root 15:1 Extract (containing withanolides) 50 mg 
A 4:1? Herbal Extract Blend of: 250 mg 
Rehmannia (Rehmannia glutinosa Root    
Chinese Yam (Dioscorea oppositifolia) Root    

Other Ingredients: Microcrystalline cellulose, cellulose, croscarmellose sodium, stearic acid (vegetable), silica, and coating (hypromellose, medium chain triglycerides, and hydroxypropylcellulose).

Directions: Take one tablet daily or as directed by your healthcare practitioner.

This product is non-GMO, gluten free, and vegetarian.

Do not use if pregnant or nursing or if you have heart disease or hypertension. Do not exceed 600 mg of glycyrrhizic acid daily. Extended use at these levels may elevate blood pressure.

Caution: If taking medication, consult your healthcare practitioner before use. Keep out of the reach of children.

Storage: Keep tightly closed in a cool, dry place.

  • Who would benefit from Licorice Plus®?

    Health care professionals typically recommend this product for cortisol metabolism support in those who are "stressed and hot" (as in feeling "burned out" by stress). This formula is designed for those who have been exposed to moderate or prolonged stress, and may have difficulty achieving an adaptive response to stress due to physically exhausted reserves.*

    How does Licorice Plus® work?

    It provides adaptogenic herbs used in traditional Chinese medicine and Ayurveda to support balanced health functions. This strategic blend is designed to support healthy cortisol metabolism (the "stress" hormone) and adrenal function (where cortisol is produced).*

    How does Licorice Plus® compare to other products or approaches?

    This product contains only natural ingredients for a safer approach. It provides botanicals with time-tested traditional use that suggest value in modern clinical experience for strategic stress response support. Herbal supplements often come with added quality concerns, but Metagenics takes added measures on all herbal products for quality assurance. Another unique product feature is standardized glycrrhizic acid to assure controlled delivery of this key active ingredient from licorice root. This formula is also suitable for vegetarian use.*

    How long is Licorice Plus® typically recommended?

    This formula was designed for strategic, short-term support for cortisol metabolism during times of stress. Individual results and recommendations may vary based on your individual needs. For best results, follow your health care professional's guidelines.*

    Why is Licorice Plus® safe?

    It contains a blend of natural ingredients with an excellent safety profile. Plus, Metagenics' manufacturing facility has 3 certifications for good manufacturing practices to ensure the highest quality. For a higher degree of reliability and predicted safety, Metagenics herbal formulas are evaluated by our MetaBotanica® Method to assure quality and the presence of active factors for optimal effectiveness.*